Tim ta 'riċerka mill-Università ta' Mie fil-Ġappun sab li l-embrijuni bikrija taż-żebrafish (embrijuni diversi sigħat wara l-fertilizzazzjoni) jistgħu jiġu irradjati b'mod sikur b'278 nm UVC.
UVC-LEDs madwar 260nm jintużaw għall-isterilizzazzjoni peress li jinduċu u jinattivaw ħsara lid-DNA minn batterji u viruses. Ħafna mir-riċerka attwali tiffoka fuq l-effett tal-UVC b'tul ta 'mewġ taħt 240nm (207nm, 222nm, 233nm) fuq il-qtil tal-koronavirus il-ġdid. Madankollu, hemm ftit studji dwar it-tossiċità, is-sigurtà, u r-rispons ta 'organiżmi għall-irradjazzjoni UVC madwar 280 nm.
Therefore, this time, a total of 16 irradiation doses were set in the range of 0.5 to 60 mJ/cm² using the irradiation device developed by the research group to irradiate 278 nm UVC, and zebrafish embryos were directly irradiated.
After 3 days of irradiation, the researchers evaluated the survival rate, hatching rate, heart rate, deformity rate, etc. of zebrafish embryos. The results found that all embryos remained alive under the irradiation dose below 4.5mJ/cm². However, when the dose reached 7.5 mJ/cm², the deformity rate significantly increased to 82 percent , and the survival rate decreased to 37 percent . Embryo death was observed if the dose was increased to 10 mJ/cm² and above.
Based on the above experimental results, the researchers determined that there is a biological defense system inside the zebrafish embryo, which can resist the damage caused by UVC irradiation to the greatest extent, and the limit dose that can resist UVC irradiation is 4.5 mJ/cm².
The researchers believe that the biological defense mechanism of zebrafish against UVC-induced DNA damage is that after zebrafish embryos are treated with UVC at a dose of 4.5 mJ/cm², the p53 signaling pathway in cells is immediately and urgently activated. Arrest, DNA repair, cell division/proliferation and damaged cell death in rapid response to stress. In addition, after 3 days of recovery, p53 variability was attenuated and instead activated the STAT signaling pathway, which continued to repair damaged DNA.
Ir-riżultati tar-riċerka ta' dan is-suġġett jipprovdu bażi xjentifika għas-sikurezza tal-UVC-LED applikati għall-ġisem tal-bniedem. Fl-istess ħin, it-tim ta 'riċerka sab li l-UVC huwa adattat għad-diżinfezzjoni ta' batterji u viruses inklużi l-koronavirus, kif ukoll id-diżinfezzjoni fl-akkwakultura.
"Experts say UV" believes that: at the application level, the sterilization experience of UVC-LED is difficult to intuitively perceive, and consumers will have concerns about safety when using it. brings confidence.
It-teknoloġija LED GMKJ hija involuta ħafna f'sorsi ta 'dawl b'saħħithom u intelliġenti, li tipprovdi lis-suq b'firxa sħiħa ta' UVA UVB UVC LED, prodotti u soluzzjonijiet infrared IR LED VCSEL, u għandha mijiet ta 'sħab ta' kwalità-għolja f'domestiċi u barranin swieq biex jippromwovu b'mod konġunt l-użu ta 'teknoloġija ħafifa biex joħolqu ħajja b'saħħitha u intelliġenti. kawża.
